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Single-pass
clot removal

because in stroke, every second matters.

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Ischemic Stroke

Results from a blood clot suddenly blocking an artery that supplies the brain.

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Without oxygen, brain tissue begins to die immediately.

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Time is Brain

A stroke progresses rapidly, killing 2 million neurons every minute.

 

Timely intervention helps minimize irreversible brain damage. 

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Greyscale imaging of brain with orange and green markers of stroke location and progression at 10 minutes

10 Minutes

Greyscale imaging of brain with orange and green markers of stroke location and progression at 60 minutes

1 Hour

Greyscale imaging of brain with orange and green markers of stroke location and progression at 3 hours

3 hours

Greyscale imaging of brain with orange and green markers of stroke location and progression at 6 hours

6 hours

Magnitude

Strokes have a significant human impact and create financial burden on society.

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4s

a patient every 4 seconds

7.8M

Global ischemic strokes per year

3.6M

global stroke deaths per year

$2.3T

Global cost of stroke by 2050

Illustration of an artery depicting a catheter catching on branch ledges

Navigability

Catheters can become stuck around branch vessels (ledge effect), which delays treatment

Illustration of a narrowing artery depicting catheter inaccessibilty to a deep blood clot

Access to the clot

Access to deeper clots often need multiple telescoping catheters in decreasing diameters

Illustration of an end-hole catheter with obstruction

suction inefficiency

Single-hole catheters aspirate slowly

and often obstruct, delaying treatment

Challenges

Thrombectomy (clot removal) with aspiration (suction) catheters is the preferred standard of care. 

 

Catheter performance is heavily impacted by complex anatomy, poor navigability and inefficient suction.

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First Pass

First-Pass Effect (FPE) is complete removal of clot in a single attempt.

 

It is a well established predictor of functional recovery after stroke.

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2x

Improved recovery

1.8x

Better NEUROLOGIC outcome

2x

Greater Functional independence

49%

Lower risk of hemorrhage

Unmet Need

Despite advances in both tools and techniques, a successful first pass occurs in less than 50% of cases today.

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SV26_Vascular Watermark_edited.jpg

Stroke Outcomes

When the first pass fails, additional attempts are needed, which prolong ischemia time and increase the risk of complications.

 

More passes are also closely associated with higher rates of mortality and long-term disability.

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20%

mortality

50%

disability

More

attempts

More

devices

MorE

time

More

risks

Longer

stay

Acute Ischemic Stroke

Occurs when a clot suddenly blocks a blood vessel supplying the brain, cutting off oxygen. Tissue begins to die within minutes. Rapid restoration of blood flow is essential to prevent irreversible damage. 

human brain glowing purple and pink

Next Generation Thrombectomy

We are working to deliver exactly that.

1.

Single-pass

Thrombectomy

2.

Consistent

clot retrieval

3.

Simplified

procedure

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